Walter Isaacson: No. Franklin had the gout and kidney stones, and he died at 84 of a ruptured lung artery, but he never had a venereal disease.
Pam’s question could be asked about a few historical personalities from the Indian subcontinent too.
NYT April 29, 2008 has an article on syphilis by MARLENE ZUK:
“…The new research suggested that syphilis originated as a skin ailment in South America, and then spread to Europe, where it became sexually transmitted and was later reintroduced to the New World.
The origin of syphilis has always held an implied accusation: if Europeans brought it to the New World, the disease is one more symbol of Western imperialism run amok, one more grudge to hold against colonialism…
… Detailed records of syphilis infection start appearing in Europe from 1495, and a fearsome disease it was. Smallpox was called smallpox to distinguish it from the great pox, syphilis, which evoked this description from Ulrich von Hutten in 1519:
“Boils that stood out like Acorns, from whence issued such filthy stinking Matter, that whosoever came within the Scent, believed himself infected. The Colour of these was of a dark Green and the very Aspect as shocking as the pain itself, which yet was as if the Sick had laid upon a fire.”…”
Jared Diamond: “…when syphilis was first definitely recorded in Europe in 1495, its pustules often covered the body from the head to the knees, caused flesh to fall off people’s faces, and led to death within a few months. By 1546, syphilis had evolved into the disease with the symptoms so well known to us today.” (Guns, Germs, and Steel, 1997)
Michael Crichton: “…You can carry tuberculosis for many decades; you can carry syphilis for a lifetime. These last are not minor diseases, but they are much less severe than they once were, because both man and organism have adapted…” (The Andromeda Strain, 1969)
This adapted syphilis might have accosted a few prominent personalities of 18th century India.
T S Shejwalkar त्र्यंबक शंकर शेजवलकर says in his classic Panipat 1761:
“Ahmad Shah Abdali probably had a disease like syphilis and so too was the case of Najib khan”.
Shejwalkar also speculates that some Maratha chieftains (most names he quotes are Brahmins) too might have suffered from the disease. These bigwigs married multiple times and also kept mistresses. One reason, he argues, they married very young girls late in their life because it was believed an intercourse with such a girl would rid them of the disease. The other possible reason was hypothesized increase in virility that came after mating with such a girl.
It is worth noting that all these Maratha bridegrooms left behind very young widows.
Even today that belief exists in parts of India: “… having sex with a ''fresh'' girl can cure syphilis, gonorrhea and other sexually transmitted diseases, including the virus that causes AIDS.” (The New York Times May 11, 1998)
My caption for picture below would read: "Hey Syphilis, Congrats now you look leaner but stronger.”
Artist: Dana Fradon The New Yorker 29 August 1959